Australian Capital Territory Numbered Regulations

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GENE TECHNOLOGY AMENDMENT REGULATION 2011 (NO 1) (NO 26 OF 2011) - REG 21

Dictionary, definition of oncogenic modification

substitute

oncogenic modification means a genetic modification capable of contributing to tumour formation, including modifications that cause at least 1 of the following:

        (a)     defects in DNA proofreading and repair;

        (b)     defects in chromosome maintenance;

        (c)     defects in cell cycle checkpoint mechanisms;

        (d)     uncontrolled cell proliferation;

        (e)     resistance to apoptosis;

        (f)     cellular immortalisation.



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